Dr.Daniel’s Asunoha.

Asunoha is a formulation, developed by the well-known phytochemist, Prof. M. Daniel and his team in Dr. Daniel’s Laboratories after extensive research, of well-known scientifically proved plants in the most effective  combination. Along with the proven anti-inflammatory herbs, other medicinal plants which are rich in antioxidants and which protect the heart, liver  and kidney as well as increasing stamina are added in this combination. The plants used in Asunoha, their active principles  and their clinically proven activities are summarized below.

  1. Amruta (Galo Tinospora cordifolia Miers) This is the well known Rasayana drug. It contains diterpenoids like columbin and chasmanthin as also an ecdysteroid. Galo exhibits significant antiarthritic, immunomodulatory, antioxidant, and anticancer properties (Prince and Co-workers, 2001).
  2. Sunthi    (Zingiber officinale Ros.) In traditional medicine, this is extensively used for its specific action in rheumatism and inflammation of liver  (Sivarajan and Balachandran,1999). It contains pungent gingerols, shogoals, glycolipids and melatonin (142ng/100g- this human hormone delays ageing and other age-related diseases like Alzheimers’s disease). Sunthi exhibits powerful  anti-inflammatory activity and is useful in arthritis and other neuromuscular problems. It protects heart, liver  and is cancer preventive (Sukhdev, 2006).
  3. Bala (Sida cordifolia L.) Since ancient times Bala was prescribed for wear and tear of the body, i.e. rheumatism. It contains β-phenethyl amines, ephedrine and mucilage. Bala is one of the acclaimed  anti-inflammatory herbs.
  4. Eranda (Ricinus communis L.)  Eranda is a reputed remedy for all kinds of rheumatic affections. The stem and roots contain two diterpenoids and tocopherol like chemical. The extract is proved anti-inflammatory (Sharma and Co-workers, 1969).
  5. Kapas beej (Gossypium herbaceum L.). In traditional medicine cotton seeds are considered an effective remedy against rheumatism (Sivarajan and Balachandran,1999).
  6. Kokilaksha (Asteracantha longifolia Nees) Kokilaksha is considered a reputed remedy for arthritis (Astanga hridaya). It contains mucilage and quinones. This plant is found to possess great antiinflammtory activities (Amin and Co-Workers, 2012) and antioxidant properties.
  7. Ashwagandha (Withania somnifera Dun.) This is a well-known tonic with great antiinflammatory, anabolic and chemopreventive properties. It contains several withanolides, sitoindisides and alkaloids. It is also immunomodulatory, reduces age related problems like Alzheimer’s and Parkinson’s diseases and is cardioprotective.
  8. Sariva (Hemidesmus indicus R.Br.) This is one of the rasayana drugs used to revitalise human body. The roots contain coumarino-lignoids such as hemidesminine. Sariva possesses great antioxidant activities and is a blood thinner. It has proven anti-inflammatory as well as hepatoprotective  activities (Prabhakaran and Co-workers , 2000).
  9. Nirgundi (Vitex negundo L.) Nirgundi is known for its efficacy in dispelling inflammatory swellings of joints in acute rheumatism. It contains monoterpenoid iridoids such as nishindaside, negundoside and flavonoids like gardenin and vitexicarpin. These compoumnds exert great anti-inflammatory, analgesic and anticancer properties (Dharmasiri and Co-workers, 2003)

From the above mentioned properties of the medicinal herbs used in this formulation it is abundantly clear that in  Asunoha we have one of the best combinations of plants traditionally used for rheumatism. All these plants are found to be experimentally effective in fighting inflammation, wear and tear of joints and other problems. Some of the plants included like Amruta, Ashwagandha, Sariva etc are well-known rasayana drugs and the chemicals in them will take care of other organs like heart, liver, kidney and circulatory system. All these plants are  rich in  antioxidants which will protect the body from chronic diseases like diabetes, cancer, stroke etc.

Rheumatism
Almost all the medical problems affecting the joints and connective tissue are included in the broad term Rheumatism, most of which are covered in the term arthritis. All these are characterized by inflammation, body pain and tiredness.
The major rheumatic disorders are the following
  1. Arthritis is a form of disorder that involves inflammation of one or more joints. There are over 100 different forms of arthritis. The most common form, osteoarthritis (degenerative joint disease), is a result of trauma to the joint (deterioration of cartilage and subchondral bone), infection of the joint, or age. Other arthritis forms are rheumatoid arthritis (disorder in which the body’s own immune system attacks body tissues), psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection.  Gout  (caused by deposition of uric acid crystals in the joint, causing inflammation- The joints in gout can often become swollen and lose function) and Infectious arthritis (a severe form of arthritis caused by bacteria elsewhere in the body) are other common forms of arthritis.
  2. Ankylosing Spondylitis is an inflammatory disease of the backbone causing chronic pain and stiffness in the middle part or the entire spine, often with pain referred to one or other buttock or the back of thigh from the sacroiliac joint.
  3. Back pain (neck pain,middle back pain,lower back pain or tailbone pain.) Back pain is the pain felt in the backside of body  that usually originates from the muscles, nerves, bones, joints or other structures in the spine.
  4. Bursitis/Tendinitis: Bursitis is the resulting pain of overusing a joint when a bursa therein becomes swollen. (Bursa is a small, fluid-filled sac that acts as a cushion between a bone and other moving body parts such as muscles, tendons, or skin) . Bursae are found throughout the body. They occur most often in the shoulder, elbow, wrist, hip, knee, or ankle.    Tendinitis is the severe swelling of a tendon (A tendon is a flexible band of tissue that connects muscles to bones. Tendons help create movement by making the muscles push or pull the bones in different ways). It can also be caused by direct trauma. It usually occurs at the knee or elbow. Tendinitis usually occurs after repeated injury to a certain area such as the wrist or ankle; e.g. tennis elbow, golfer’s elbow, pitcher’s shoulder, swimmer’s shoulder, and jumper’s knee.
  5. Capsulitis involves inflammation of ligaments and joints. E.g. Neck pain.

The medicines recommended for almost all rheumatic disorders are pain-killers and in some cases,  corticosteroids. But in Ayurvedic system of medicine there are excellent remedies which alleviate the suffering due to rheumatism.