Asunoha is a formulation, developed by the well-known phytochemist, Prof. M. Daniel and his team in Dr. Daniel’s Laboratories after extensive research, of well-known scientifically proved plants in the most effective combination. Along with the proven anti-inflammatory herbs, other medicinal plants which are rich in antioxidants and which protect the heart, liver and kidney as well as increasing stamina are added in this combination. The plants used in Asunoha, their active principles and their clinically proven activities are summarized below.
- Amruta (Galo– Tinospora cordifolia Miers) This is the well known Rasayana drug. It contains diterpenoids like columbin and chasmanthin as also an ecdysteroid. Galo exhibits significant antiarthritic, immunomodulatory, antioxidant, and anticancer properties (Prince and Co-workers, 2001).
- Sunthi (Zingiber officinale Ros.) In traditional medicine, this is extensively used for its specific action in rheumatism and inflammation of liver (Sivarajan and Balachandran,1999). It contains pungent gingerols, shogoals, glycolipids and melatonin (142ng/100g- this human hormone delays ageing and other age-related diseases like Alzheimers’s disease). Sunthi exhibits powerful anti-inflammatory activity and is useful in arthritis and other neuromuscular problems. It protects heart, liver and is cancer preventive (Sukhdev, 2006).
- Bala (Sida cordifolia L.) Since ancient times Bala was prescribed for wear and tear of the body, i.e. rheumatism. It contains β-phenethyl amines, ephedrine and mucilage. Bala is one of the acclaimed anti-inflammatory herbs.
- Eranda (Ricinus communis L.) Eranda is a reputed remedy for all kinds of rheumatic affections. The stem and roots contain two diterpenoids and tocopherol like chemical. The extract is proved anti-inflammatory (Sharma and Co-workers, 1969).
- Kapas beej (Gossypium herbaceum L.). In traditional medicine cotton seeds are considered an effective remedy against rheumatism (Sivarajan and Balachandran,1999).
- Kokilaksha (Asteracantha longifolia Nees) Kokilaksha is considered a reputed remedy for arthritis (Astanga hridaya). It contains mucilage and quinones. This plant is found to possess great antiinflammtory activities (Amin and Co-Workers, 2012) and antioxidant properties.
- Ashwagandha (Withania somnifera Dun.) This is a well-known tonic with great antiinflammatory, anabolic and chemopreventive properties. It contains several withanolides, sitoindisides and alkaloids. It is also immunomodulatory, reduces age related problems like Alzheimer’s and Parkinson’s diseases and is cardioprotective.
- Sariva (Hemidesmus indicus R.Br.) This is one of the rasayana drugs used to revitalise human body. The roots contain coumarino-lignoids such as hemidesminine. Sariva possesses great antioxidant activities and is a blood thinner. It has proven anti-inflammatory as well as hepatoprotective activities (Prabhakaran and Co-workers , 2000).
- Nirgundi (Vitex negundo L.) Nirgundi is known for its efficacy in dispelling inflammatory swellings of joints in acute rheumatism. It contains monoterpenoid iridoids such as nishindaside, negundoside and flavonoids like gardenin and vitexicarpin. These compoumnds exert great anti-inflammatory, analgesic and anticancer properties (Dharmasiri and Co-workers, 2003)
From the above mentioned properties of the medicinal herbs used in this formulation it is abundantly clear that in Asunoha we have one of the best combinations of plants traditionally used for rheumatism. All these plants are found to be experimentally effective in fighting inflammation, wear and tear of joints and other problems. Some of the plants included like Amruta, Ashwagandha, Sariva etc are well-known rasayana drugs and the chemicals in them will take care of other organs like heart, liver, kidney and circulatory system. All these plants are rich in antioxidants which will protect the body from chronic diseases like diabetes, cancer, stroke etc.